An antimorphic mutant of Brh2 resulting from a conservative amino acid change within the BRC element
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Brh2, the streamlined BRCA2 family protein from Ustilago maydis, directs homologous recombination by modulating Rad51 filament dynamics through a single BRC element. Here, we describe an unusual antimorphic mutation within the BRC β-hairpin of Brh2, in which ... ...
