Dihydroorotate dehydrogenase: A multifunctional target in cancer, infectious diseases, and immune disorders
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Pyrimidine is required for the biosynthesis of DNA, RNA, glycoproteins, and phospholipids. Dihydroorotate dehydrogenase (DHODH) is a crucial flavin-dependent enzyme in mitochondria involved in the de novo pyrimidine synthesis and has been considered a signific... ...
