Overexpression of Thioredoxin-1 alleviates morphine-induced neuroinflammation in BV-2 cells and the ventral tegmental area of mice
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The clinical utility of morphine is limited by the development of tolerance and addiction. These processes are linked to neuroinflammation involved microglial responses. Thioredoxin-1 (Trx-1) is a crucial endogenous antioxidant with neuroprotective properties,... ...
