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Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse

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Donor-derived CD19-CAR T cells offer a therapeutic option for B cell malignancies relapsing after allogeneic hematopoietic stem cell transplantation but are often constrained by poor engraftment, expansion, and persistence. In a first-in-human study (NCT010872... ...