Synthesis of new 2-styryl-3-nitroimidazo[1,2-a]pyridine derivatives via base-induced elimination of 2-N-tosyl intermediates and in vitro antileishmanial evaluation
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To explore the antileishmanial structure-activity relationships in a 3-nitroimidazo[1,2-a]pyridine series, we developed a previously undescribed olefination strategy at position 2 via elimination of intermediates bearing an N-tosyl group, giving access to E-co... ...
