Cu(OTf)2-catalyzed access to 2,4,5-trisubstituted imidazoles from acyclic Reissert compounds
{{output}}
A Cu(OTf)2-catalyzed cascade self-coupling of N-acyl-α-aminonitriles (acyclic Reissert compounds) has been developed to afford 2,4,5-trisubstituted imidazoles in moderate to good yields. Single-crystal X-ray diffraction confirmed the structure of a representa... ...
