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A preliminary investigation of the effects of amentoflavone on TNF-α-induced endothelial activation in HUVECs

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Background: Endothelial dysfunction characterized by cytokine release and adhesion molecule upregulation is a major driver of atherogenesis. Tumor necrosis factor-α (TNF-α) activates NF-κB signaling and increases ICAM-1, VCAM-... ...