x-Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+-Stabilized Expanded Active-Site Cleft Adapted for Phospholipid Binding
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Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, ... ...
