3-Deoxy-4-sulfonamido-butein derivatives promote cell cycle arrest and apoptosis by inhibiting EGFR/JAK2/STAT3 signaling in A549 lung cancer cells
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Butein, a naturally occurring chalcone, exhibits diverse pharmacological potential but suffers from limited anticancer efficacy. To address this limitation and improve drug-likeness, we designed and synthesized a novel series of 3-deoxy-4-sulfonamido-butein de... ...
