Combined Nivolumab and Ipilimumab Therapy Promotes Immune-Mediated Cardiomyocyte Apoptosis Through TLR4-Myd88-NF- Κ b-Driven Activation of the NLRP3 Inflammasome
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Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but are associated with serious immune-related cardiac toxicities. In this study, AC16 human cardiomyocytes were exposed to nivolumab alone or in combination with ipilimumab. The expressi... ...
