Effects of nocturnal melatonin-based tissue-bone homeostasis manipulation at varying time points on pain and central mechanisms in individuals with knee osteoarthritis: a randomized controlled trial
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Background: Tissue-bone homeostasis manipulation (TBHM) has been proven effective for knee osteoarthritis (KOA), but its optimal timing and underlying mechanisms remain unclear. Melatonin serves as a key biomarker of circadian rh... ...
