Stem cell-derived extracellular vesicles -mediated bone regeneration: mechanisms, targeted delivery, and clinical perspectives in promoting angiogenesis
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Angiogenesis is indispensable for bone regeneration and tightly coupled to osteogenesis, yet inadequate vascularization remains a common cause of repair failure in critical-sized defects, compromised fractures, and osteochondral lesions. Conventional growth-fa... ...