Emerging chemical strategies for CD38 inhibition: restoring NAD+ metabolism and disease control
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Cluster of differentiation 38 (CD38) is a multifunctional ectoenzyme regulating immune functions, calcium signaling, and nicotinamide adenine dinucleotide (NAD+) metabolism. Through rapid hydrolytic degradation of NAD+, CD38 drives cellular NAD+ depletion duri... ...
