Endothelial RhoA is essential for embryonic and postnatal vascular development by regulating KLF2-Notch1 signaling
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The small GTPase RhoA has diverse cellular functions, including in actin fiber reorganization. However, its role in angiogenesis remains elusive. To reveal this, we generated mice with endothelium-specific constitutive or tamoxifen-inducible conditional knocko... ...