Structure and function of the L-MYC N-terminus impacts strategies to inhibit the MYC family of oncoproteins
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The MYC family of transforming oncogenes function as regulators of gene transcription and is composed of three members, MYC, MYCN and MYCL. As c-MYC (MYC) is deregulated in >50% of human cancers, the role, regulation and structural features of MYC have been we... ...
