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Modeling smooth muscle cell endothelial cell crosstalk in abdominal aortic aneurysms using 3D microvessels on-chip

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Abdominal aortic aneurysms (AAA) are pathological dilations of the abdominal aorta. To date, surgical intervention is the only option for managing large AAAs, with no pharmacological therapies to prevent growth of small aneurysms. A current limitation in inves... ...