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Antimelanoma Activity of the Mastoparan Peptides MPX and MP1: Cellular Selectivity and Mechanism of Action

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MPX (Mastoparan X) and MP1 (Polybia-MP1) are cationic amphiphilic peptides isolated from the venom of insects of the Vespidae family. Due to their physicochemical features, these peptides show affinity for biomimetic membranes, especially the more anionic ones... ...