Engineering of the glucose uptake system to increase 2,4-Dihydroxybutyric acid production in Escherichia coli
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2,4-Dihydroxybutyric acid (DHB) is a promising C4 platform compound for the synthesis of methionine analogues and biodegradable polymers. However, aerobic DHB production from glucose in Escherichia coli involves transient acetate overflow prior to product synt... ...