Organocatalytic asymmetric [4+4]-annulation reaction between ynones and benzylidene thiazolones: synthesis of eight-membered ether containing 4,5-fused thiazoles
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An asymmetric (4+4)-annulation of benzylidene thiazolones and ynones by aminocatalysis is described. An enantioselective synthesis of eight-membered ether embedded 4,5-fused thiazoles is reported for the first time in this work. The reaction's scope is wide, ... ...
