Combining Engineered Probe Library with Tiered Screening for the Rational Discovery of Alzheimer's Diagnostic Probe with an Enhanced Signal-to-Noise Ratio
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Alzheimer's disease (AD) is neuropathologically defined by the deposition of β-amyloid (Aβ) plaques, a key diagnostic biomarker. However, current fluorescence probes targeting Aβ plaques are often limited by poor blood-brain barrier (BBB) penetration and s... ...
