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A JAK of two trades: beneficial or adverse effects of Janus kinase inhibition for plasma LDL-cholesterol and major adverse cardiovascular events in inflammatory bowel disease patients?

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Purpose of review: Janus kinase (JAK) inhibitors have emerged as potent anti-inflammatory drugs and are prescribed in rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). However, cardiovascular safety concerns have em... ...