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Magnetic Metal-Organic Framework (MOF)-Mediated Precision Capture of Mitochondria Reveals Subcellular Metabolic and Lipid Remodeling of Crabtree Effect in Yeast

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Crabtree effect, defined as the propensity of yeast to prioritize fermentation over respiration in high-glucose environments, is a classic metabolic adaptation. However, the limitations of conventional mitochondrial isolation methods have hindered in-depth inv... ...