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Zinc (II)-Chelation-Enhanced Spectrofluorimetric Determination of Moxifloxacin: Development, Validation, Application to Eye Drops, and Greenness Assessment

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A sensitive and straightforward spectrofluorimetric method was developed for determination of moxifloxacin (MOX) based on its complexation with zinc ion (Zn2+) in acetate buffer (pH 5). A formation of the MOX-Zn chelate produced a pronounced fluorescence enhan... ...