A positive feedback loop between TKT and c-Myc drives TACE resistance in hepatocellular carcinoma
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Hepatocellular carcinoma (HCC) often receives transarterial chemoembolization (TACE), yet clinical benefit is limited by resistance driven by ischemia-induced adaptations. This study explains how transketolase (TKT) in the pentose phosphate pathway (PPP) modul... ...
