Activation of nociceptin receptor attenuates methamphetamine motivation and relapse in rats: Involvement of phosphorylated CREB and Akt in the nucleus accumbens
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Accumulating evidence has highlighted the functional role of the endogenous nociceptin/orphanin FQ peptide (N/OFQ) and its nociceptin opioid receptor (NOP) in alcohol and cocaine reward. However, the effects of NOP agonists on methamphetamine (MAP) reinforceme... ...
