Deubiquitinase USP43 exacerbates myocardial ischemia-reperfusion injury by stabilizing ASK1 and activating the JNK/P38 MAPK pathway
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Myocardial ischemia-reperfusion injury (MIRI) remains a major challenge in reperfusion therapy for acute myocardial infarction. The role of deubiquitinating enzyme ubiquitin-specific protease 43 (USP43) in this process, however, remains largely unexplored. In ... ...