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Single-molecule force spectroscopy discovers a dual-binding mode in the hCG-mediated activation of LHCGR

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Human Chorionic Gonadotropin (hCG) mediates the activation of luteinizing hormone/choriogonadotropin receptor (LHCGR) by binding to it, which is critical for human reproduction. However, specific dynamics of such interaction remain ambiguous. Herein, we utiliz... ...