A Cu-based metal-organic framework based on desloratadine and siHIF-1α for achievement of genes/drugs/CDT combination therapy in hepatocellular carcinoma
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Background: Desloratadine (DL) has been demonstrated to inhibit NMT1 enzymatic activity, thereby promoting oxidative stress and endoplasmic reticulum (ER) stress to induce cancer cell death. However, the lack of tumor targeting l... ...