Comparative validation of oxidative bisulfite sequencing (oxBS) and chemical-assisted pyridine borane sequencing (CAPS) protocols for locus-specific 5-hydroxymethylcytosine quantification
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Background: DNA methylation is a key regulator of tissue-specific gene expression, cell differentiation, and development. In mammals, DNA methylation predominantly occurs as 5-methylcytosine (5mC) at CpG dinucleotides. DNA methyl... ...
