Persistent Loss of Intrahepatic IFN-γ in HBV Is Linked to Selective Impairment of Liver-Resident CXCR6+NK Cells Despite Long-Term NUC Therapy
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Background and aims: Chronic hepatitis B virus (HBV) infection remains incurable in most patients despite long-term nucleos(t)ide analogue (NUC) therapy. Interferon-γ (IFN-γ) is a cornerstone of antiviral immunity, but its in s... ...