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A New Era in Leptomeningeal Disease (LMD): Recent Advancements in Immunocellular and Radiation Therapies in Melanoma LMD, What Has Been Done and Future Directions

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Leptomeningeal disease (LMD) or leptomeningeal metastases (LM) occurs when tumor cells invade the leptomeningeal and cerebrospinal fluid (CSF) space. Melanoma is the most common cancer causing LMD (M-LMD). Its biology and pathophysiology are very poorly unders... ...