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Early-onset PUFA deficiency exacerbates lean MAFLD-like hepatic injury in FADS2 knockout mice

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Polyunsaturated fatty acids (PUFAs) are vital for maintaining health, particularly during infancy and early childhood. In this study, we examined PUFA deficiency in FADS2 knockout (KO) mice, which lack endogenous synthesis of PUFAs with ≥20 carbons, by feedin... ...