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Resveratrol modulates Hedgehog signaling pathway and increases the osteogenic commitment of periodontal ligament mesenchymal cells

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Human periodontal ligament mesenchymal cells (PDLCs) are promising for regenerative therapies but show heterogeneous osteogenic commitment that limits bone regeneration. To attempt to overcome this limitation, we focus on the Hedgehog (Hh) signaling pathway, w... ...