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Novel glyceryl ascorbate derivatives inhibit type 2 alarmin cytokine induction and promote expression of epidermal barrier function-related factors in human keratinocytes in vitro

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Atopic dermatitis is characterized by the interplay among type 2 immune responses, skin barrier dysfunction, and pruritus. Despite the pivotal role of interleukin-33 in the pathogenesis of the disease, novel therapeutic strategies remain limited. In this study... ...