Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab-binding domain
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TBC (Tre2/Bub2/Cdc16) domain-containing proteins constitute the widespread family of GTPase-activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Sh... ...
