Effects and Mechanisms of Nobiletin on Gut Motility by Coordinating Bile Acid Signaling via Dual Ileal-Colonic Axes in STC Model Mice
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Slow transit constipation (STC) is a functional gastrointestinal disorder with complex etiology and limited therapeutic options. Nobiletin (NOB), a natural polymethoxyflavone derived from citrus, exhibits multiple pharmacological activities. However, its effec... ...