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EBV encoded tegument protein BKRF4 suppresses RLR signaling pathway-mediated interferon production through inhibiting the activation of IRF3 and IRF7

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Epstein-Barr virus (EBV), a member of gamma herpesvirus subfamily, infects more than 90% of the people in the world. There are some studies on EBV-mediated regulation of type I interferon (IFN-I) signaling, however, the underlying mechanism is still not fully ... ...