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Pyrazoline-Imidazopyridine Hybrids as Beclin-1 Mimetics Driving Dual Apoptotic and Autophagy in Breast Cancer

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Breast cancer is a profound cause of mortality among women globally. Similar to BH3 mimetics, targeting the antiapoptotic Bcl-xL:Beclin1 protein complex is crucial to inducing apoptosis and autophagy, thereby suppressing tumor progression in breast cancer cell... ...