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T‑Cell Immunoreceptor with Ig and Immunoreceptor Tyrosine-Based Inhibitory Motif Domains/Cluster of Differentiation 40 Cellular Nanovesicles Carrying Oxaliplatin Exhibited Superior Pancreatic Cancer Cells Therapy

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Profound chemoresistance and a highly immunosuppressive tumor microenvironment (TME) contribute to the high mortality rate of pancreatic ductal adenocarcinoma (PDAC). The overexpression of CD155 in PDAC facilitates its binding to the inhibitory receptor T-cell... ...