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SIRT1 plays a critical role in maintaining the viability of Yak Sertoli cells by regulating mitochondrial biogenesis via activating the PGC-1α-NRF-1-TFAM pathway

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Objective: Sertoli cells are somatic cells located within the seminiferous tubules that play a critical role in spermatogenesis through various mechanisms, such as paracrine signaling and the formation of the blood-testis barrier... ...