Nuclear localization signals (NLSs) endowed the dual-specificity protein phosphatase-4 (DUSP4) of Crassostrea gigas with a novel dephosphorylation function
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Dual-specificity protein phosphatase 4 (DUSP4), a critical negative regulator of the mitogen-activated protein kinase (MAPK) signaling pathway, enters the nucleus via conserved nuclear localization sequences (NLS) to dephosphorylate key kinases in vertebrates.... ...