HIF-mediated regulation of glutathione-specific gamma-glutamyl cyclotransferase 1 contributes to tubular cell death in renal ischemia-reperfusion
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Renal ischemia-reperfusion (I/R) remains a leading cause of acute renal failure in both native and transplanted kidneys. Hypoxia-inducible factor (HIF)-1α is a protective factor against renal I/R injury (rIRI). However, the downstream mechanisms through which... ...
