PARP7 inhibition and a STING agonist potentiate radiation-induced immunogenicity in glioblastoma
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Glioblastoma (GBM) is the most lethal form of brain cancer with an immunosuppressive tumor microenvironment (TME). Radio- and chemotherapy can modify the TME and elicit anti-tumor immunity through the STING and type I interferon (IFN-I) pathways. STING agonist... ...
