Design, synthesis, and radioprotection activity evaluation of 1H-1,2,3-triazole derivatives as TLR2/1 small molecule agonists
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Toll-like receptors (TLRs), a family of pattern recognition receptors of the innate immune system, have been shown to exert radioprotective effects by activating the NF-κB signaling pathway. In this context, we designed and synthesized a series of novel TLR2/... ...
