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FcγRIIb deficiency inhibits tumor development by attenuating the immunosuppressive phenotype of MDSCs

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Regulation of myeloid-derived suppressor cell (MDSC) programming is critical for controlling tumor growth and anti-tumor immune responses. The role of FcγRIIb in MDSC programming was examined. FcγRIIb deficiency was found to promote MDSC differentiation and ... ...