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A human-relevant epithelial-fibroblast co-culture platform for integrated analysis of PHMG-HCl-induced pulmonary fibrogenic responses

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Polyhexamethylene guanidine hydrochloride (PHMG-HCl) is a fibrogenic chemical associated with severe pulmonary injury, however, human-relevant in vitro systems capable of mechanistically evaluating fibrogenic responses remain limited. Pulmonary fibrosis is dri... ...