In Silico-Identified Peptides of Five Borrelia burgdorferi Proteins Binding with High Affinity to Human Leukocyte Antigen (HLA) Class II Alleles
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To date, Lyme vaccine development has largely overlooked the vaccinee's human leukocyte antigen (HLA) genetic makeup on which antibody production critically depends. Here, we evaluated in silico the predicted binding affinities of 192 HLA-II alleles with all ... ...