Computational and experimental targeting of TraH-TraU interaction in Acinetobacter baumannii inhibits type IV secretion system (T4SS) mediated transfer of the tetracycline resistance gene
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Antimicrobial resistance genes are transferred through conjugation-based horizontal gene transfer, which relies on the type IV secretion system (T4SS) for DNA transfer. Thus, conjugation inhibitors hold promise for controlling the spread of resistance genes am... ...
