MYC and AP-1 oncogenes cooperatively bind enhancers to rewire transcription
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The transcription factor c-MYC (MYC) is deregulated in ~70% of human cancers. Through de novo motif discovery analysis on published MYC ChIP-seq datasets from cancer cell lines, we found cell-type-specific co-enrichment of the TRE motifs (AP-1 binding sites) a... ...
