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GPR176 represses mitophagy to promote the progression of osteosarcoma by facilitating mTORC1 activity via PI3K-AKT pathway

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Background: Osteosarcoma (OS) is a common primary malignant tumor of the bone. It is reported that abnormal GPR176 expression contributes to the occurrence and subsequent progression of tumors. However, the role of GPR176 in OS h... ...